The main risk is increased hypoglycaemia, requiring frequent blood glucose monitoring and insulin dose adjustments
After month 3, weight loss velocity often plateaus slightly as your body reaches a new equilibrium at the current dose
While GLP-1 receptor agonists like semaglutide have been widely studied for their effects on appetite and blood sugar, the addition of GIP receptor activation introduces a second metabolic pathway that may influence insulin sensitivity, energy regulation, and even how the body handles dietary fat
While many patients tolerate GLP-1 medications well, some may experience mild side effects as their body adjusts: Nausea Digestive changes, like feeling full more quickly Occasional fatigue These effects usually lessen over time
Fatigue : About 7% of individuals report feeling tired or weak, often due to reduced caloric intake
They dont address whats happening at the tissue level the cellular damage, the inflammation that wont shut off, the collagen that stopped rebuilding, the nerve signals that keep firing after the original injury is long gone
